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IACCIICD-10: M79.7
Fibromyalgia
Chronic widespread pain disorder with fatigue, cognitive difficulties, and sleep disturbances.
US Prevalence
10.0M
estimated affected individuals
Annual New Cases
500.0K
new diagnoses per year
Diagnostic Delay
5 years
average time to diagnosis
Annual Cost / Patient
$10,000
national burden: $100B+ estimated
Key Facts
Critical data points clinicians and policymakers should know
- ~10 million Americans affected
- Women are 2x more likely to be diagnosed
- Significant overlap with ME/CFS and Long COVID
- Average 5-year diagnostic delay
- No definitive diagnostic test
Related Symptoms
8 documented symptoms across 5 body systems
3
neurological
- Brain Fog / Cognitive Dysfunction
- Sleep Disruption
- Numbness / Tingling
2
musculoskeletal
- Joint Pain / Arthralgia
- Muscle Pain / Myalgia
1
systemic
- Chronic Fatigue
1
psychiatric
- Depression
1
sensory
- Light Sensitivity
Symptom Overlap with Other Conditions
Conditions that share symptoms with Fibromyalgia, ranked by number of shared symptoms. High overlap can contribute to misdiagnosis and diagnostic delay.
Lyme Disease7 shared
88% of Fibromyalgia symptomsChronic FatigueBrain Fog / Cognitive DysfunctionJoint Pain / ArthralgiaMuscle Pain / MyalgiaNumbness / TinglingDepressionLight Sensitivity
Long COVID7 shared
88% of Fibromyalgia symptomsChronic FatigueBrain Fog / Cognitive DysfunctionJoint Pain / ArthralgiaMuscle Pain / MyalgiaSleep DisruptionNumbness / TinglingDepression
ME/CFS7 shared
88% of Fibromyalgia symptomsChronic FatigueBrain Fog / Cognitive DysfunctionJoint Pain / ArthralgiaMuscle Pain / MyalgiaSleep DisruptionDepressionLight Sensitivity
POTS3 shared
38% of Fibromyalgia symptomsChronic FatigueBrain Fog / Cognitive DysfunctionSleep Disruption
Severity at a Glance
Comparative metrics placing Fibromyalgia in context
Long COVID18.0M
Fibromyalgia (this condition)10.0M
ME/CFS3.3M
POTS3.0M
Lyme Disease2.0M
Alpha-gal Syndrome450.0K
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Data sourced from CDC, Census Bureau (HPS), CMS, NIH, AHRQ, and peer-reviewed literature. Last updated August 2026.