Loading InvisibleSignal...

Medication & Supplement Tracker

Track medications, supplements, and potential interactions for invisible illness management

Disclaimer: This information is for educational purposes only. It does not constitute medical advice. Always consult your healthcare provider before starting, stopping, or changing any medication or supplement.

Avg. Medications

5.3

Per invisible illness patient

Polypharmacy Rate

42%

Patients on 5+ concurrent medications

Avg. Monthly Cost

$340

Out-of-pocket medication expenses

My Medications

Add Medication

Select from Database

Or Custom Entry

Dosage

Frequency

Start Date

Notes

No medications tracked yet.

Add medications above to track and check interactions.

Common Medications by Condition

Doxycycline

Lyme

Doxycycline hyclate

Tetracycline antibiotic

Common Side Effects

PhotosensitivityNauseaEsophageal irritationDiarrhea

Key Interaction Warnings

Antacids reduce absorption
Warfarin effect increased
Oral contraceptive efficacy reduced

Amoxicillin

Lyme

Amoxicillin trihydrate

Penicillin antibiotic

Common Side Effects

DiarrheaRashNauseaYeast infections

Key Interaction Warnings

Methotrexate toxicity increased
Allopurinol increases rash risk
May reduce oral contraceptive efficacy

Cefuroxime

Lyme

Cefuroxime axetil

Cephalosporin antibiotic

Common Side Effects

DiarrheaNauseaHeadacheVaginitis

Key Interaction Warnings

Probenecid increases levels
Aminoglycosides increase nephrotoxicity risk
Antacids reduce absorption

Azithromycin

Lyme

Azithromycin dihydrate

Macrolide antibiotic

Common Side Effects

DiarrheaNauseaAbdominal painQT prolongation

Key Interaction Warnings

Warfarin effect increased
Digoxin levels increased
Avoid with other QT-prolonging drugs

Paxlovid (early treatment)

Long COVID

Nirmatrelvir/ritonavir

Protease inhibitor combination

Common Side Effects

Dysgeusia (altered taste)DiarrheaHypertensionMyalgia

Key Interaction Warnings

Major CYP3A interactions — contraindicated with many drugs
Statins must be paused
Immunosuppressants require dose adjustment

Low-dose Naltrexone (LDN)

Long COVID

Naltrexone hydrochloride

Opioid antagonist (off-label immunomodulator)

Common Side Effects

Vivid dreamsHeadacheNauseaInsomnia

Key Interaction Warnings

Contraindicated with opioid medications
May reduce efficacy of opioid-based cough suppressants
Avoid with Tramadol

CoQ10

Long COVID

Coenzyme Q10 (ubiquinone)

Mitochondrial supplement

Common Side Effects

Mild GI upsetInsomnia at high dosesHeadache

Key Interaction Warnings

May reduce Warfarin efficacy
Statin drugs deplete CoQ10 — supplementation often recommended
May lower blood pressure additively with antihypertensives

NAC

Long COVID

N-Acetyl Cysteine

Mucolytic / antioxidant

Common Side Effects

NauseaVomitingDiarrheaRash

Key Interaction Warnings

May enhance nitroglycerin effects
Activated charcoal reduces absorption
May interfere with some lab tests

Rintatolimod (Ampligen)

ME/CFS

Rintatolimod

Immunomodulator (dsRNA)

Common Side Effects

Flu-like symptomsInjection site reactionsChillsFatigue flare

Key Interaction Warnings

Limited data — discuss all medications with prescriber
May enhance interferon effects

LDN (for ME/CFS)

ME/CFS

Naltrexone hydrochloride

Opioid antagonist (off-label)

Common Side Effects

Vivid dreamsHeadacheMild nauseaSleep disturbance

Key Interaction Warnings

Contraindicated with opioids
Avoid Tramadol
Timing matters — typically taken at bedtime

B12 Injections

ME/CFS

Cyanocobalamin / Methylcobalamin

Vitamin supplement

Common Side Effects

Injection site painMild diarrheaItchingHeadache

Key Interaction Warnings

Metformin reduces B12 absorption
Proton pump inhibitors reduce B12 levels
Colchicine may reduce absorption

D-Ribose

ME/CFS

D-Ribose

Energy substrate supplement

Common Side Effects

Hypoglycemia at high dosesNauseaDiarrheaHeadache

Key Interaction Warnings

May lower blood glucose — monitor with insulin or diabetes medications
No major known drug interactions

Duloxetine (Cymbalta)

Fibromyalgia

Duloxetine hydrochloride

SNRI antidepressant

Common Side Effects

NauseaDry mouthDrowsinessConstipationDizziness

Key Interaction Warnings

Serotonin syndrome risk with SSRIs/triptans/MAOIs
CYP1A2 inhibitors increase levels
Avoid abrupt discontinuation

Pregabalin (Lyrica)

Fibromyalgia

Pregabalin

Gabapentinoid / anticonvulsant

Common Side Effects

DizzinessDrowsinessWeight gainPeripheral edemaBlurred vision

Key Interaction Warnings

CNS depressants (additive sedation)
Opioids increase respiratory depression risk
ACE inhibitors may increase angioedema risk

Milnacipran

Fibromyalgia

Milnacipran hydrochloride

SNRI

Common Side Effects

NauseaHeadacheConstipationDizzinessHot flashes

Key Interaction Warnings

Serotonin syndrome risk with other serotonergic drugs
MAOIs contraindicated
May increase blood pressure — monitor with antihypertensives

Amitriptyline

Fibromyalgia

Amitriptyline hydrochloride

Tricyclic antidepressant

Common Side Effects

DrowsinessDry mouthWeight gainConstipationBlurred vision

Key Interaction Warnings

MAOIs contraindicated
QT prolongation risk with other cardiac drugs
CYP2D6 inhibitors increase levels
Additive sedation with CNS depressants

Fludrocortisone

POTS

Fludrocortisone acetate

Mineralocorticoid

Common Side Effects

Fluid retentionHypokalemiaHeadacheWeight gain

Key Interaction Warnings

NSAIDs increase fluid retention
Potassium-depleting diuretics worsen hypokalemia
Digoxin toxicity risk with low potassium

Midodrine

POTS

Midodrine hydrochloride

Alpha-1 agonist (vasopressor)

Common Side Effects

Supine hypertensionPiloerection (goosebumps)Urinary retentionScalp tingling

Key Interaction Warnings

Beta-blockers may reduce efficacy
Digoxin may cause bradycardia
Avoid with MAOIs
Do not take within 4 hours of bedtime

Ivabradine

POTS

Ivabradine hydrochloride

If-channel blocker

Common Side Effects

BradycardiaVisual disturbances (phosphenes)HeadacheDizziness

Key Interaction Warnings

CYP3A4 inhibitors increase levels
Beta-blockers additive bradycardia
Avoid grapefruit juice
QT-prolonging drugs increase risk

Salt Tablets

POTS

Sodium chloride

Electrolyte supplement

Common Side Effects

GI upsetBloatingIncreased blood pressure at high doses

Key Interaction Warnings

May counteract antihypertensive drugs
Lithium levels affected by sodium intake
Monitor with mineralocorticoids (additive sodium retention)

Epinephrine Auto-Injector

Alpha-gal

Epinephrine (adrenaline)

Sympathomimetic

Common Side Effects

TachycardiaTremorAnxietyHeadachePallor

Key Interaction Warnings

Beta-blockers reduce effectiveness
Tricyclic antidepressants potentiate cardiac effects
MAOIs increase hypertensive risk

Cetirizine

Alpha-gal

Cetirizine hydrochloride

H1 antihistamine

Common Side Effects

DrowsinessDry mouthFatigueHeadache

Key Interaction Warnings

CNS depressants (additive sedation)
Alcohol increases drowsiness
Theophylline may slightly increase cetirizine levels

Famotidine

Alpha-gal

Famotidine

H2 antihistamine

Common Side Effects

HeadacheDizzinessConstipationDiarrhea

Key Interaction Warnings

Reduces absorption of ketoconazole, itraconazole
Reduces absorption of atazanavir
May affect pH-dependent drug absorption

Supplement Guide for Invisible Illness

Vitamin D3

Immune modulation, bone health, fatigue reduction

2,000-5,000 IU/day

Test 25-OH levels first. Common deficiency in chronic illness. Take with fat-containing meal.

Magnesium Glycinate

Muscle relaxation, sleep, nerve function

200-400 mg/day

Glycinate form best tolerated. Helps with fibromyalgia pain and sleep. Avoid oxide form (poor absorption).

Omega-3 (EPA/DHA)

Anti-inflammatory, cardiovascular, cognitive support

1,000-3,000 mg EPA+DHA/day

Choose molecularly distilled, third-party tested. May increase bleeding risk with anticoagulants.

Probiotics

Gut microbiome support, immune modulation

10-50 billion CFU/day

Multi-strain formulas preferred. Especially important during/after antibiotic therapy. Refrigerated strains often more viable.

Curcumin (Turmeric)

Anti-inflammatory, antioxidant

500-1,500 mg/day

Requires piperine or liposomal form for absorption. May interact with blood thinners.

Alpha Lipoic Acid

Neuropathy support, antioxidant, blood sugar regulation

300-600 mg/day

R-form is more bioavailable. May lower blood sugar — monitor with diabetes medications.

L-Glutathione

Master antioxidant, detoxification support

250-500 mg/day

Liposomal or acetylated forms preferred for oral bioavailability. NAC is a precursor alternative.

Electrolyte Mixes

Hydration, POTS symptom management

1-3 servings/day

Critical for POTS patients. Look for formulas with sodium, potassium, and magnesium. Avoid high-sugar options.

Your medication data is stored locally in your browser and never sent to our servers. You can export your list by copying it from your browser's developer tools.

Explore Related Modules

Treatment Guide

Evidence-based treatment info

Provider Directory

Find specialists near you

Symptom Journal

Track symptoms over time

Data Sources (7)

U.S. Food and Drug Administration (FDA). FDA Drug Safety Communications and Labeling Changes. 2024-2026.
National Library of Medicine, National Institutes of Health (NIH). DailyMed — FDA-Approved Drug Labeling. 2026.
Drugs.com (Cerner Multum / IBM Micromedex). Drugs.com Clinical Drug Interaction Database. 2026.
National Institutes of Health (NIH/NCCIH). NIH National Center for Complementary and Integrative Health: Dietary Supplements. 2025.
Centers for Disease Control and Prevention (CDC). CDC Lyme Disease Treatment Guidance. 2025.
National Institutes of Health (NIH). RECOVER Initiative — Long COVID Clinical Trial Data. 2025-2026.
Journal of General Internal Medicine. Polypharmacy in Chronic Fatigue and Fibromyalgia: A Cross-Sectional Analysis. 2024.

Medication & Supplement Tracker

Track medications, supplements, and potential interactions for invisible illness management

Avg. Medications

5.3

Per invisible illness patient

Polypharmacy Rate

42%

Patients on 5+ concurrent medications

Avg. Monthly Cost

$340

Out-of-pocket medication expenses

My Medications

Add Medication

Select from Database

Or Custom Entry

Dosage

Frequency

Start Date

Notes

No medications tracked yet.

Add medications above to track and check interactions.

Common Medications by Condition

Doxycycline

Lyme

Doxycycline hyclate

Tetracycline antibiotic

Common Side Effects

PhotosensitivityNauseaEsophageal irritationDiarrhea

Key Interaction Warnings

Antacids reduce absorption
Warfarin effect increased
Oral contraceptive efficacy reduced

Amoxicillin

Lyme

Amoxicillin trihydrate

Penicillin antibiotic

Common Side Effects

DiarrheaRashNauseaYeast infections

Key Interaction Warnings

Methotrexate toxicity increased
Allopurinol increases rash risk
May reduce oral contraceptive efficacy

Cefuroxime

Lyme

Cefuroxime axetil

Cephalosporin antibiotic

Common Side Effects

DiarrheaNauseaHeadacheVaginitis

Key Interaction Warnings

Probenecid increases levels
Aminoglycosides increase nephrotoxicity risk
Antacids reduce absorption

Azithromycin

Lyme

Azithromycin dihydrate

Macrolide antibiotic

Common Side Effects

DiarrheaNauseaAbdominal painQT prolongation

Key Interaction Warnings

Warfarin effect increased
Digoxin levels increased
Avoid with other QT-prolonging drugs

Paxlovid (early treatment)

Long COVID

Nirmatrelvir/ritonavir

Protease inhibitor combination

Common Side Effects

Dysgeusia (altered taste)DiarrheaHypertensionMyalgia

Key Interaction Warnings

Major CYP3A interactions — contraindicated with many drugs
Statins must be paused
Immunosuppressants require dose adjustment

Low-dose Naltrexone (LDN)

Long COVID

Naltrexone hydrochloride

Opioid antagonist (off-label immunomodulator)

Common Side Effects

Vivid dreamsHeadacheNauseaInsomnia

Key Interaction Warnings

Contraindicated with opioid medications
May reduce efficacy of opioid-based cough suppressants
Avoid with Tramadol

CoQ10

Long COVID

Coenzyme Q10 (ubiquinone)

Mitochondrial supplement

Common Side Effects

Mild GI upsetInsomnia at high dosesHeadache

Key Interaction Warnings

May reduce Warfarin efficacy
Statin drugs deplete CoQ10 — supplementation often recommended
May lower blood pressure additively with antihypertensives

NAC

Long COVID

N-Acetyl Cysteine

Mucolytic / antioxidant

Common Side Effects

NauseaVomitingDiarrheaRash

Key Interaction Warnings

May enhance nitroglycerin effects
Activated charcoal reduces absorption
May interfere with some lab tests

Rintatolimod (Ampligen)

ME/CFS

Rintatolimod

Immunomodulator (dsRNA)

Common Side Effects

Flu-like symptomsInjection site reactionsChillsFatigue flare

Key Interaction Warnings

Limited data — discuss all medications with prescriber
May enhance interferon effects

LDN (for ME/CFS)

ME/CFS

Naltrexone hydrochloride

Opioid antagonist (off-label)

Common Side Effects

Vivid dreamsHeadacheMild nauseaSleep disturbance

Key Interaction Warnings

Contraindicated with opioids
Avoid Tramadol
Timing matters — typically taken at bedtime

B12 Injections

ME/CFS

Cyanocobalamin / Methylcobalamin

Vitamin supplement

Common Side Effects

Injection site painMild diarrheaItchingHeadache

Key Interaction Warnings

Metformin reduces B12 absorption
Proton pump inhibitors reduce B12 levels
Colchicine may reduce absorption

D-Ribose

ME/CFS

D-Ribose

Energy substrate supplement

Common Side Effects

Hypoglycemia at high dosesNauseaDiarrheaHeadache

Key Interaction Warnings

May lower blood glucose — monitor with insulin or diabetes medications
No major known drug interactions

Duloxetine (Cymbalta)

Fibromyalgia

Duloxetine hydrochloride

SNRI antidepressant

Common Side Effects

NauseaDry mouthDrowsinessConstipationDizziness

Key Interaction Warnings

Serotonin syndrome risk with SSRIs/triptans/MAOIs
CYP1A2 inhibitors increase levels
Avoid abrupt discontinuation

Pregabalin (Lyrica)

Fibromyalgia

Pregabalin

Gabapentinoid / anticonvulsant

Common Side Effects

DizzinessDrowsinessWeight gainPeripheral edemaBlurred vision

Key Interaction Warnings

CNS depressants (additive sedation)
Opioids increase respiratory depression risk
ACE inhibitors may increase angioedema risk

Milnacipran

Fibromyalgia

Milnacipran hydrochloride

SNRI

Common Side Effects

NauseaHeadacheConstipationDizzinessHot flashes

Key Interaction Warnings

Serotonin syndrome risk with other serotonergic drugs
MAOIs contraindicated
May increase blood pressure — monitor with antihypertensives

Amitriptyline

Fibromyalgia

Amitriptyline hydrochloride

Tricyclic antidepressant

Common Side Effects

DrowsinessDry mouthWeight gainConstipationBlurred vision

Key Interaction Warnings

MAOIs contraindicated
QT prolongation risk with other cardiac drugs
CYP2D6 inhibitors increase levels
Additive sedation with CNS depressants

Fludrocortisone

POTS

Fludrocortisone acetate

Mineralocorticoid

Common Side Effects

Fluid retentionHypokalemiaHeadacheWeight gain

Key Interaction Warnings

NSAIDs increase fluid retention
Potassium-depleting diuretics worsen hypokalemia
Digoxin toxicity risk with low potassium

Midodrine

POTS

Midodrine hydrochloride

Alpha-1 agonist (vasopressor)

Common Side Effects

Supine hypertensionPiloerection (goosebumps)Urinary retentionScalp tingling

Key Interaction Warnings

Beta-blockers may reduce efficacy
Digoxin may cause bradycardia
Avoid with MAOIs
Do not take within 4 hours of bedtime

Ivabradine

POTS

Ivabradine hydrochloride

If-channel blocker

Common Side Effects

BradycardiaVisual disturbances (phosphenes)HeadacheDizziness

Key Interaction Warnings

CYP3A4 inhibitors increase levels
Beta-blockers additive bradycardia
Avoid grapefruit juice
QT-prolonging drugs increase risk

Salt Tablets

POTS

Sodium chloride

Electrolyte supplement

Common Side Effects

GI upsetBloatingIncreased blood pressure at high doses

Key Interaction Warnings

May counteract antihypertensive drugs
Lithium levels affected by sodium intake
Monitor with mineralocorticoids (additive sodium retention)

Epinephrine Auto-Injector

Alpha-gal

Epinephrine (adrenaline)

Sympathomimetic

Common Side Effects

TachycardiaTremorAnxietyHeadachePallor

Key Interaction Warnings

Beta-blockers reduce effectiveness
Tricyclic antidepressants potentiate cardiac effects
MAOIs increase hypertensive risk

Cetirizine

Alpha-gal

Cetirizine hydrochloride

H1 antihistamine

Common Side Effects

DrowsinessDry mouthFatigueHeadache

Key Interaction Warnings

CNS depressants (additive sedation)
Alcohol increases drowsiness
Theophylline may slightly increase cetirizine levels

Famotidine

Alpha-gal

Famotidine

H2 antihistamine

Common Side Effects

HeadacheDizzinessConstipationDiarrhea

Key Interaction Warnings

Reduces absorption of ketoconazole, itraconazole
Reduces absorption of atazanavir
May affect pH-dependent drug absorption

Supplement Guide for Invisible Illness

Vitamin D3

Immune modulation, bone health, fatigue reduction

2,000-5,000 IU/day

Test 25-OH levels first. Common deficiency in chronic illness. Take with fat-containing meal.

Magnesium Glycinate

Muscle relaxation, sleep, nerve function

200-400 mg/day

Glycinate form best tolerated. Helps with fibromyalgia pain and sleep. Avoid oxide form (poor absorption).

Omega-3 (EPA/DHA)

Anti-inflammatory, cardiovascular, cognitive support

1,000-3,000 mg EPA+DHA/day

Choose molecularly distilled, third-party tested. May increase bleeding risk with anticoagulants.

Probiotics

Gut microbiome support, immune modulation

10-50 billion CFU/day

Multi-strain formulas preferred. Especially important during/after antibiotic therapy. Refrigerated strains often more viable.

Curcumin (Turmeric)

Anti-inflammatory, antioxidant

500-1,500 mg/day

Requires piperine or liposomal form for absorption. May interact with blood thinners.

Alpha Lipoic Acid

Neuropathy support, antioxidant, blood sugar regulation

300-600 mg/day

R-form is more bioavailable. May lower blood sugar — monitor with diabetes medications.

L-Glutathione

Master antioxidant, detoxification support

250-500 mg/day

Liposomal or acetylated forms preferred for oral bioavailability. NAC is a precursor alternative.

Electrolyte Mixes

Hydration, POTS symptom management

1-3 servings/day

Critical for POTS patients. Look for formulas with sodium, potassium, and magnesium. Avoid high-sugar options.

Your medication data is stored locally in your browser and never sent to our servers. You can export your list by copying it from your browser's developer tools.

Explore Related Modules

Treatment Guide

Evidence-based treatment info

Provider Directory

Find specialists near you

Symptom Journal

Track symptoms over time

Data Sources (7)

U.S. Food and Drug Administration (FDA). FDA Drug Safety Communications and Labeling Changes. 2024-2026.
National Library of Medicine, National Institutes of Health (NIH). DailyMed — FDA-Approved Drug Labeling. 2026.
Drugs.com (Cerner Multum / IBM Micromedex). Drugs.com Clinical Drug Interaction Database. 2026.
National Institutes of Health (NIH/NCCIH). NIH National Center for Complementary and Integrative Health: Dietary Supplements. 2025.
Centers for Disease Control and Prevention (CDC). CDC Lyme Disease Treatment Guidance. 2025.
National Institutes of Health (NIH). RECOVER Initiative — Long COVID Clinical Trial Data. 2025-2026.
Journal of General Internal Medicine. Polypharmacy in Chronic Fatigue and Fibromyalgia: A Cross-Sectional Analysis. 2024.